Nmu^em1(cre)Zak
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nmu^em1(cre)Zak
• Name: neuromedin U; endonuclease-mediated mutation 1, Zachary Knight
• MGI ID: MGI:8272210
• Gene: Nmu Location: Chr5:76481342-76511624 bp, - strand Genetic Position: Chr5, 40.93 cM
• Alliance: Nmu^em1(cre)Zak page

Mutation origin

• Strain of Origin: FVB/NJ

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Nmu^em1(cre)Zak expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nmu (MGI:1860476)

• Mutation details: The allele was created using homologous recombination, aided by targeted CRISPR/cas9 endonuclease activity, to insert a viral 2A oligopeptide sequence (T2A; mediates ribosomal skipping) and a Cre recombinase gene just upstream of the endogenous Stop codon of the Nmu gene. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nmu (mouse) Summary of all recombinase alleles driven by Nmu. Alliance mouse Nmu gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nmu Mutation: 18 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)