Ndnf^tm1(flpo)Rwt
Targeted Allele Detail

Summary

• Symbol: Ndnf^tm1(flpo)Rwt
• Name: neuron-derived neurotrophic factor; targeted mutation 1, Richard W Tsien
• MGI ID: MGI:8268620
• Synonyms: Ndnf-Flp
• Gene: Ndnf Location: Chr6:65648595-65689307 bp, + strand Genetic Position: Chr6, 30.29 cM
• Alliance: Ndnf^tm1(flpo)Rwt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:349470
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Ndnf^tm1(flpo)Rwt expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ndnf (MGI:1915419)

• Mutation details: A T2A-flpo-polyA cassette was inserted immediately following the last codon of the open reading frame via homologous recombination. (J:349470)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Ndnf (mouse) Summary of all recombinase alleles driven by Ndnf. Alliance mouse Ndnf gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ndnf Mutation: 30 strains or lines available

References

• Original: J:349470 Chamberland S, et al., Functional specialization of hippocampal somatostatin-expressing interneurons. Proc Natl Acad Sci U S A. 2024 Apr 23;121(17):e2306382121
• All: 1 reference(s)