Kmt2d^em2Kaig
Endonuclease-mediated Allele Detail

Summary

• Symbol: Kmt2d^em2Kaig
• Name: lysine (K)-specific methyltransferase 2D; endonuclease-mediated mutation 1, Kai Ge
• MGI ID: MGI:8266896
• Gene: Kmt2d Location: Chr15:98729550-98769085 bp, - strand
• Alliance: Kmt2d^em2Kaig page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1

Mutation description

• Allele Type: Endonuclease-mediated (Inducible degradation)
• Mutation: Insertion
• Mutation details:

  Using CRISPR/Cas9 endonuclease-mediated genome editing, a single guide RNA (5'-TGTCCATCCCTCTCTCCGAC-3') was used to insert a minimal auxin-inducible degron sequence after the start codon located on exon 2 of the lysine (K)-specific methyltransferase 2D (Kmt2d) gene. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Kmt2d Mutation: 171 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)