Med13l^em7Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Med13l^em7Lutzy
• Name: mediator complex subunit 13-like; endonuclease-mediated mutation 7, Cathy Lutz
• MGI ID: MGI:8263059
• Gene: Med13l Location: Chr5:118698744-118903503 bp, + strand Genetic Position: Chr5, 59.1 cM
• Alliance: Med13l^em7Lutzy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Humanized sequence)
• Mutation: Nucleotide substitutions
• Mutation details: This CRISPR/cas9 mediated mutation has exon 21 replaced with the sequence of human exon 21 with a Q1537* nonsense mutation found to be pathogenic in human (J:101977)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Med13l Mutation: 118 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)