Znhit3^em2Dean
Endonuclease-mediated Allele Detail

Summary

• Symbol: Znhit3^em2Dean
• Name: zinc finger, HIT type 3; endonuclease-mediated mutation 2, Jurrien Dean
• MGI ID: MGI:8263000
• Synonyms: Znhit3 KO
• Gene: Znhit3 Location: Chr11:84801776-84807192 bp, - strand Genetic Position: Chr11, 51.34 cM
• Alliance: Znhit3^em2Dean page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 genome editing technology was used to generate a 1060 bp deletion in the gene, including 32 bp in the protein coding sequence. (J:374974)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Znhit3 Mutation: 15 strains or lines available

References

• Original: J:374974 Yang G, et al., ZNHIT3 Regulates Translation to Ensure Cell Lineage Differentiation in Mouse Preimplantation Development. Adv Sci (Weinh). 2025 Jun;12(21):e2413599
• All: 1 reference(s)