Avpr1a^em1(cre)Zell
Endonuclease-mediated Allele Detail

Summary

• Symbol: Avpr1a^em1(cre)Zell
• Name: arginine vasopressin receptor 1A; endonuclease-mediated mutation 1, Lori M Zeltser
• MGI ID: MGI:8262983
• Synonyms: Avpr1a-Cre
• Gene: Avpr1a Location: Chr10:122284404-122289357 bp, + strand Genetic Position: Chr10, 70.36 cM, cytoband D3
• Alliance: Avpr1a^em1(cre)Zell page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Avpr1a^em1(cre)Zell expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Avpr1a (MGI:1859216)

• A P2A-cre construct was inserted in-frame via CRISPR/cas9 mediated recombination (J:374722)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Avpr1a (mouse) Summary of all recombinase alleles driven by Avpr1a. Alliance mouse Avpr1a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Avpr1a Mutation: 40 strains or lines available

References

• Original: J:374722 Francois M, et al., Amygdala AVPR1A mediates susceptibility to chronic social isolation in female mice. Nat Commun. 2025 Nov 4;16(1):9740
• All: 1 reference(s)