Ppid^em1Ppgr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppid^em1Ppgr
• Name: peptidylprolyl isomerase D (cyclophilin D); endonuclease-mediated mutation 1, Pere Puigserver
• MGI ID: MGI:8262524
• Synonyms: PPID^fl, PPID^flox
• Gene: Ppid Location: Chr3:79498649-79510957 bp, + strand Genetic Position: Chr3, 34.91 cM, cytoband F1
• Alliance: Ppid^em1Ppgr page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• LoxP sites were inserted to flank exon 4. (J:373627)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppid Mutation: 25 strains or lines available

References

• Original: J:373627 Latorre-Muro P, et al., Chaperone-mediated insertion of mitochondrial import receptor TOM70 protects against diet-induced obesity. Nat Cell Biol. 2025 Jan;27(1):130-140
• All: 1 reference(s)