Trpm5^em1(cre)Taru
Endonuclease-mediated Allele Detail

Summary

• Symbol: Trpm5^em1(cre)Taru
• Name: transient receptor potential cation channel, subfamily M, member 5; endonuclease-mediated mutation 1, Akiyuki Taruno
• MGI ID: MGI:8261243
• Synonyms: Trpm5^Cre
• Gene: Trpm5 Location: Chr7:142625266-142648379 bp, - strand Genetic Position: Chr7, 88.11 cM
• Alliance: Trpm5^em1(cre)Taru page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout, Recombinase)
• Mutation: Insertion
• Trpm5^em1(cre)Taru expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Trpm5 (MGI:1861718)

• Mutation details: CRISPR/cas9-mediated recombination replaces the initial ATG with a cre gene with a triplet of the nuclear localization signal peptide from the SV40 large T antigen. (J:365727)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Trpm5 (mouse) Summary of all recombinase alleles driven by Trpm5. Alliance mouse Trpm5 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trpm5 Mutation: 58 strains or lines available

References

• Original: J:365727 Soma S, et al., Channel synapse mediates neurotransmission of airway protective chemoreflexes. Cell. 2025 Apr 2
• All: 1 reference(s)