Zic1^em1(cre)Mbgr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zic1^em1(cre)Mbgr
• Name: zinc finger protein of the cerebellum 1; endonuclease-mediated mutation 1, Matthew B Greenblatt
• MGI ID: MGI:8259257
• Synonyms: Zic1-cre
• Gene: Zic1 Location: Chr9:91240111-91247863 bp, - strand Genetic Position: Chr9, 48.26 cM
• Alliance: Zic1^em1(cre)Mbgr page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Zic1^em1(cre)Mbgr expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Zic1 (MGI:106683)

• Mutation details: CRISPR/cas9-mediated recombination inserted a cre-rBG-pA cassette into exon 1 adjacent to the untranslated region. (J:347266)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Zic1 (mouse) Summary of all recombinase alleles driven by Zic1. Alliance mouse Zic1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zic1 Mutation: 34 strains or lines available

References

• Original: J:347266 Sun J, et al., A vertebral skeletal stem cell lineage driving metastasis. Nature. 2023 Sep;621(7979):602-609
• All: 1 reference(s)