Csf1r^{em1(dre/ERT2)Shej}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Csf1r^{em1(dre/ERT2)Shej}
• Name: colony stimulating factor 1 receptor; endonuclease-mediated mutation 1, Jianpeng Sheng
• MGI ID: MGI:8258024
• Gene: Csf1r Location: Chr18:61238644-61264211 bp, + strand Genetic Position: Chr18, 34.41 cM, cytoband D
• Alliance: Csf1r^{em1(dre/ERT2)Shej} page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Csf1r^{em1(dre/ERT2)Shej} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Csf1r (MGI:1339758)

• CRISPR/cas9-mediated recombination inserted a dre/ERT2-WPRE-PA cassette into exon 1. (J:343376)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Csf1r (mouse) Summary of all recombinase alleles driven by Csf1r. Alliance mouse Csf1r gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csf1r Mutation: 70 strains or lines available

References

• Original: J:343376 Zhao YX, et al., Single-cell RNA sequencing-guided fate-mapping toolkit delineates the contribution of yolk sac erythro-myeloid progenitors. Cell Rep. 2023 Nov 28;42(11):113364
• All: 1 reference(s)