Hbb-bh1^em1(cre)Shej
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hbb-bh1^em1(cre)Shej
• Name: hemoglobin Z, beta-like embryonic chain; endonuclease-mediated mutation 1, Jianpeng Sheng
• MGI ID: MGI:8258022
• Gene: Hbb-bh1 Location: Chr7:103490845-103492369 bp, - strand Genetic Position: Chr7, 54.85 cM
• Alliance: Hbb-bh1^em1(cre)Shej page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Hbb-bh1^em1(cre)Shej expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hbb-bh1 (MGI:96024)

• CRISPR/cas9-mediated recombination inserted an IRES-cre cassette in the 3' UTR. (J:343376)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hbb-bh1 (mouse) Summary of all recombinase alleles driven by Hbb-bh1. Alliance mouse Hbb-bh1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hbb-bh1 Mutation: 7 strains or lines available

References

• Original: J:343376 Zhao YX, et al., Single-cell RNA sequencing-guided fate-mapping toolkit delineates the contribution of yolk sac erythro-myeloid progenitors. Cell Rep. 2023 Nov 28;42(11):113364
• All: 1 reference(s)