Cdh9^{em1(icre)Phpo}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cdh9^{em1(icre)Phpo}
• Name: cadherin 9; endonuclease-mediated mutation 1, Polyxeni Philippidou
• MGI ID: MGI:8254781
• Synonyms: Cdh9^iCre
• Gene: Cdh9 Location: Chr15:16728842-16857180 bp, + strand Genetic Position: Chr15, 7.91 cM
• Alliance: Cdh9^{em1(icre)Phpo} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Cdh9^{em1(icre)Phpo} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Cdh9 (MGI:107433)

• Mutation details: CRISPR/cas9-mediated recombination inserted a P2A-icre cassette in place of the stop codon in exon 12. (J:369068)
• Inheritance: Not Specified

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cdh9 (mouse) Summary of all recombinase alleles driven by Cdh9. Alliance mouse Cdh9 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cdh9 Mutation: 46 strains or lines available

References

• Original: J:369068 Vagnozzi AN, et al., Coordinated cadherin functions sculpt respiratory motor circuit connectivity. Elife. 2022 Dec 30;11
• All: 1 reference(s)