Mir33^em2.1Cfh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir33^em2.1Cfh
• Name: microRNA 33; endonuclease-mediated mutation 2.1, Carlos Fernandez-Hernando
• MGI ID: MGI:8253305
• Synonyms: miR-33^loxP
• Gene: Mir33 Location: Chr15:82082323-82082391 bp, + strand Genetic Position: Chr15, 38.54 cM
• Alliance: Mir33^em2.1Cfh page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed the microRNA. Flp-mediated recombination removed the selection cassette. (J:302582)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir33 Mutation: 1 strain or line available

References

• Original: J:302582 Price NL, et al., Loss of hepatic miR-33 improves metabolic homeostasis and liver function without altering body weight or atherosclerosis. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2006478118
• All: 3 reference(s)