Tg(Defa24-icre)1Clib
Transgene Detail

Summary

• Symbol: Tg(Defa24-icre)1Clib
• Name: transgene insertion 1, Claude Libert
• MGI ID: MGI:8249482
• Transgene: Tg(Defa24icre)1Clib Location: unknown
• Alliance: Tg(Defa24-icre)1Clib page

Transgene origin

• Strain of Origin: C57BL/6J

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Defa24-icre)1Clib expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Defa24 (MGI:3630383)

• Mutation details: An iCre gene into the coding region of the C57BL/6J Defa24 gene in a BAC clone, which was injected into zygote pro-nuclei. Four transgenic lines were established, but only one with expression selectively in Paneth cells was chosen for further analysis. (J:370139)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Defa24 (mouse) Summary of all recombinase alleles driven by Defa24. Alliance mouse Defa24 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:370139 Garcia-Gonzalez N, et al., Generation of a new Paneth cell-specific Cre-recombinase transgenic mouse line. Front Immunol. 2025;16:1576995
• All: 1 reference(s)