Gfi1^{em1(cre)Zyliu}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gfi1^{em1(cre)Zyliu}
• Name: growth factor independent 1 transcription repressor; endonuclease-mediated mutation 1, Zhiyong Liu
• MGI ID: MGI:8249359
• Synonyms: Gfi1^HA-Cre
• Gene: Gfi1 Location: Chr5:107864521-107873671 bp, - strand Genetic Position: Chr5, 52.23 cM
• Alliance: Gfi1^{em1(cre)Zyliu} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, No functional change, Recombinase)
• Mutation: Insertion
• Gfi1^{em1(cre)Zyliu} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gfi1 (MGI:103170)

• Mutation details: The Gfi1 gene 5' end of the coding region was tagged with 3x hemagglutinin (HA) encoding fragments and followed by a 2a-cre cassette. (J:368975)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gfi1 (mouse) Summary of all recombinase alleles driven by Gfi1. Alliance mouse Gfi1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gfi1 Mutation: 32 strains or lines available

References

• Original: J:368975 Wang G, et al., Deciphering the genetic interactions between Pou4f3, Gfi1, and Rbm24 in maintaining mouse cochlear hair cell survival. Elife. 2024 Mar 14;12
• All: 1 reference(s)