Foxc2^{tm1(icre/ERT2)Bcgen}
Targeted Allele Detail

Summary

• Symbol: Foxc2^{tm1(icre/ERT2)Bcgen}
• Name: forkhead box C2; targeted mutation 1, Biocytogen LLC
• MGI ID: MGI:8249339
• Synonyms: Foxc2^iCreERT2
• Gene: Foxc2 Location: Chr8:121842910-121845634 bp, + strand Genetic Position: Chr8, 70.33 cM
• Alliance: Foxc2^{tm1(icre/ERT2)Bcgen} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:360839
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Foxc2^{tm1(icre/ERT2)Bcgen} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Foxc2 (MGI:1347481)

• An icre/ERT2 construct was inserted in the gene. (J:360839)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Foxc2 (mouse) Summary of all recombinase alleles driven by Foxc2. Alliance mouse Foxc2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Foxc2 Mutation: 17 strains or lines available

References

• Original: J:360839 Wang Z, et al., Identification of quiescent FOXC2(+) spermatogonial stem cells in adult mammals. Elife. 2023 Aug 23;12
• All: 1 reference(s)