Gal^{em1(flpo)Jkohl}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gal^{em1(flpo)Jkohl}
• Name: galanin and GMAP prepropeptide; endonuclease-mediated mutation 1, Johannes Kohl
• MGI ID: MGI:8249263
• Gene: Gal Location: Chr19:3459915-3464544 bp, - strand Genetic Position: Chr19, 3.16 cM
• Alliance: Gal^{em1(flpo)Jkohl} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Gal^{em1(flpo)Jkohl} expression driven by 2 genes
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Gal (MGI:95637)
  mouse	Gal (MGI:95637)

• CRISPR-targeting inserted a P2A-flpo recombinase 3' of the Stop codon in exon 6. (J:342490)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Gal (mouse) Summary of all recombinase alleles driven by Gal. Alliance mouse Gal gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gal Mutation: 22 strains or lines available

References

• Original: J:342490 Ammari R, et al., Hormone-mediated neural remodeling orchestrates parenting onset during pregnancy. Science. 2023 Oct 6;382(6666):76-81
• All: 1 reference(s)