Rab23^tm1.1Elkg
Targeted Allele Detail

Summary

• Symbol: Rab23^tm1.1Elkg
• Name: RAB23, member RAS oncogene family; targeted mutation 1.1, Eyleen LK Goh
• MGI ID: MGI:8249197
• Synonyms: Rab23^f, Rab23-floxed
• Gene: Rab23 Location: Chr1:33758991-33781642 bp, + strand Genetic Position: Chr1, 12.8 cM
• Alliance: Rab23^tm1.1Elkg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:274715
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exon 4 was flanked by loxP sites. An inserted neomycin selection cassette was removed via flp-mediated recombination. (J:274715)

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab23 Mutation: 33 strains or lines available

References

• Original: J:274715 Hor CHH, et al., Rab23 Regulates Radial Migration of Projection Neurons via N-cadherin. Cereb Cortex. 2018 Apr 1;28(4):1516-1531
• All: 3 reference(s)