Triml2^em1(cre)Bryd
Endonuclease-mediated Allele Detail

Summary

• Symbol: Triml2^em1(cre)Bryd
• Name: tripartite motif family-like 2; endonuclease-mediated mutation 1, Elizabeth Bryda
• MGI ID: MGI:8249172
• Synonyms: Triml2-P2A-Cre-Myc
• Gene: Triml2 Location: Chr8:43633578-43646918 bp, + strand Genetic Position: Chr8, 23.89 cM
• Alliance: Triml2^em1(cre)Bryd page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Epitope tag, Recombinase)
• Mutation: Insertion
• Triml2^em1(cre)Bryd expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Triml2 (MGI:3642989)

• Mutation details: CRISPR/Cas9 genome editing technology was used to replace the endogenous STOP codon of the gene with a P2A-Cre-Myc cassette. (J:353974)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Triml2 (mouse) Summary of all recombinase alleles driven by Triml2. Alliance mouse Triml2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Triml2 Mutation: 24 strains or lines available

References

• Original: J:353974 Davis DJ, et al., Efficient DNA knock-in using AAV-mediated delivery with 2-cell embryo CRISPR-Cas9 electroporation. Front Genome Ed. 2023;5:1256451
• All: 1 reference(s)