Dbh^{em1(cre/ERT2)Miyk}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dbh^{em1(cre/ERT2)Miyk}
• Name: dopamine beta hydroxylase; endonuclease-mediated mutation 1, Kazunari Miyamichi
• MGI ID: MGI:8248020
• Synonyms: DBH-CreER^T2
• Gene: Dbh Location: Chr2:27055519-27073216 bp, + strand Genetic Position: Chr2, 19.29 cM
• Alliance: Dbh^{em1(cre/ERT2)Miyk} page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Dbh^{em1(cre/ERT2)Miyk} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Dbh (MGI:94864)

• Mutation details: An IRES-CreERT2 cassette was inserted just after the coding end of exon 12 using CRISPR genome editing technology. (J:360768)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Dbh (mouse) Summary of all recombinase alleles driven by Dbh. Alliance mouse Dbh gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dbh Mutation: 15 strains or lines available

References

• Original: J:360768 Harima Y, et al., Parallel labeled-line organization of sympathetic outflow for selective organ regulation in mice. Nat Commun. 2024 Dec 10;15(1):10478
• All: 1 reference(s)