Avp^{tm1.1(flpo)Gdol}
Targeted Allele Detail

Summary

• Symbol: Avp^{tm1.1(flpo)Gdol}
• Name: arginine vasopressin; targeted mutation 1.1, Gul Dolen
• MGI ID: MGI:8246762
• Gene: Avp Location: Chr2:130422540-130424474 bp, - strand Genetic Position: Chr2, 63.24 cM
• Alliance: Avp^{tm1.1(flpo)Gdol} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Avp^{tm1.1(flpo)Gdol} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Avp (MGI:88121)

• Mutation details: The targeting vector was designed to replace the stop codon of the arginine vasopressin (Avp) gene, with a 2A-Flp cassette. The targeting construct included a 2A peptide sequence followed by a codon-optimized Flp recombinase sequence and a LoxP-flanked neomycin cassette. Cre recombinase removed the neomycin cassette. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Avp (mouse) Summary of all recombinase alleles driven by Avp. Alliance mouse Avp gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Avp Mutation: 19 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)