Slc6a9^{em1(icre)Mira}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc6a9^{em1(icre)Mira}
• Name: solute carrier family 6 (neurotransmitter transporter, glycine), member 9; endonuclease-mediated mutation 1, Manuel Miranda
• MGI ID: MGI:8246644
• Gene: Slc6a9 Location: Chr4:117692240-117726502 bp, + strand Genetic Position: Chr4, 53.62 cM
• Alliance: Slc6a9^{em1(icre)Mira} page

Mutation origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1/J

Mutation description

• Allele Type: Endonuclease-mediated (Recombinase)
• Mutation: Insertion
• Slc6a9^{em1(icre)Mira} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Slc6a9 (MGI:95760)

• Mutation details: Using CRISPR/Cas9 endonuclease-mediated genome editing, guide RNAs were used to introduce a P2A peptide, followed by codon-optimized iCre-recombinase and polyA sequences, into exon 14 of the solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (Slc6a9) gene. (J:101977)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Slc6a9 (mouse) Summary of all recombinase alleles driven by Slc6a9. Alliance mouse Slc6a9 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc6a9 Mutation: 26 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)