Nr2f2^{tm1(icre/ERT2)Hy}
Targeted Allele Detail

Summary

• Symbol: Nr2f2^{tm1(icre/ERT2)Hy}
• Name: nuclear receptor subfamily 2, group F, member 2; targeted mutation 1, Humphrey Yao
• MGI ID: MGI:8244861
• Synonyms: Nr2f2-T2A-iCreERT2
• Gene: Nr2f2 Location: Chr7:70001692-70016483 bp, - strand Genetic Position: Chr7, 38.66 cM
• Alliance: Nr2f2^{tm1(icre/ERT2)Hy} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:371597
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Inducible, Null/knockout, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Nr2f2^{tm1(icre/ERT2)Hy} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Nr2f2 (MGI:1352452)

• A T2A-iCreERT2 cassette was inserted into exon 3 at the stop codon. (J:371597)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nr2f2 (mouse) Summary of all recombinase alleles driven by Nr2f2. Alliance mouse Nr2f2 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr2f2 Mutation: 28 strains or lines available

References

• Original: J:371597 Brown PR, et al., Generation of a Nr2f2-driven inducible Cre mouse to target interstitial cells in the reproductive system. Biol Reprod. 2025 Apr 18
• All: 1 reference(s)