Pafah1b3^em1(IMPC)Bay
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pafah1b3^em1(IMPC)Bay
• Name: platelet-activating factor acetylhydrolase, isoform 1b, subunit 3; endonuclease-mediated mutation 1, Baylor College of Medicine
• MGI ID: MGI:8244294
• Gene: Pafah1b3 Location: Chr7:24994473-24997377 bp, - strand Genetic Position: Chr7, 13.73 cM, cytoband A3
• Alliance: Pafah1b3^em1(IMPC)Bay page
• IMPC: Pafah1b3 gene page

Mutation origin

• Strain of Origin: C57BL/6N
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated at Baylor College of Medicine using Cas9 and guides with spacer sequences CAACTTCGAGTAAACCCAAC and CTTGCATTCCCTTGGGCAAC that targeted exon(s) ENSMUSE00000199497.4 ENSMUSE00000840883.2 ENSMUSE00001220612.2 ENSMUSE00001758088.1 ENSMUSE00002148855.1. This resulted in deletion(s) of 1126 bp (location: Chr7:24995116-24996241; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pafah1b3 Mutation: 12 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 2 reference(s)