Pilra^em1Asw
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pilra^em1Asw
• Name: paired immunoglobin-like type 2 receptor alpha; endonuclease-mediated mutation 1, Anand Swaroop
• MGI ID: MGI:8242351
• Synonyms: Pilra^-
• Gene: Pilra Location: Chr5:137820214-137834540 bp, - strand Genetic Position: Chr5, 76.77 cM
• Alliance: Pilra^em1Asw page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR-targeting generated a 1610 bp deletion that removes exon 1 and a part of exon 2 of the Pilra gene. (J:363577)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pilra Mutation: 28 strains or lines available

References

• Original: J:286045 Li YT, et al., Blood flow guides sequential support of neutrophil arrest and diapedesis by PILR-beta1 and PILR-alpha. Elife. 2019 Aug 6;8:e47642
• All: 2 reference(s)