Dlx4^tm1.1Mso
Targeted Allele Detail

Summary

• Symbol: Dlx4^tm1.1Mso
• Name: distal-less homeobox 4; targeted mutation 1.1, Maria I Morasso
• MGI ID: MGI:8240278
• Synonyms: Dlx4 KO
• Gene: Dlx4 Location: Chr11:95031273-95037089 bp, - strand Genetic Position: Chr11, 59.01 cM
• Alliance: Dlx4^tm1.1Mso page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:366598
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT site, lacZ, loxP site, neomycin resistance gene, second FRT site and second loxP site were inserted upstream of exon 2 and a third loxP site were inserted downstream of exon 2. Cre-mediated recombination removed the neomycin selection gene and exon 2, leaving lacZ. (J:366598)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dlx4 Mutation: 7 strains or lines available

References

• Original: J:366598 Bhattacharya S, et al., Homeobox transcription factor DLX4 is not necessary for skin development and homeostasis. Exp Dermatol. 2018 Mar;27(3):289-292
• All: 1 reference(s)