Ttn^tm1(TTN)Cya
Targeted Allele Detail

Summary

• Symbol: Ttn^tm1(TTN)Cya
• Name: titin; targeted mutation 1, Cyagen Biosciences
• MGI ID: MGI:8235735
• Synonyms: Ttn^tm1(hTTN)
• Gene: Ttn Location: Chr2:76534324-76812891 bp, - strand Genetic Position: Chr2, 45.13 cM, cytoband D
• Alliance: Ttn^tm1(TTN)Cya page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:326541
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Ttn^tm1(TTN)Cya expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Ttn (MGI:98864)

• Mutation details: The sequence from the ATG start codon to the TAA stop codon of mouse gene was replaced with the sequence from the ATG start codon to the TAA stop codon of human gene. (J:326541)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ttn Mutation: 1456 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)