Rbpms2^tm1.1Thbr
Targeted Allele Detail

Summary

• Symbol: Rbpms2^tm1.1Thbr
• Name: RNA binding protein with multiple splicing 2; targeted mutation 1.1, Thomas Braun
• MGI ID: MGI:8226419
• Synonyms: Rbpms2-LacZ
• Gene: Rbpms2 Location: Chr9:65536930-65567810 bp, + strand Genetic Position: Chr9, 35.43 cM
• Alliance: Rbpms2^tm1.1Thbr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:369747
• Parent Cell Line: v6.5 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Part of exon 2 was replaced with a lacZ-pA-FRT-PGKneo-FRT cassette via homologous recombination. Flp mediated recombination removed the neo cassette. (J:369747)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbpms2 Mutation: 202 strains or lines available

References

• Original: J:369747 Lin S, et al., Rbpms2 prevents major cardiac defects in cardiomyocyte-specific Rbpms-deficient mice. Dev Cell. 2025 Jun 24
• All: 1 reference(s)