Gm2044^em1Meli
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gm2044^em1Meli
• Name: predicted gene 2044; endonuclease-mediated mutation 1, Meng Liang
• MGI ID: MGI:8205456
• Gene: Gm2044 Location: Chr7:139536897-139537983 bp, - strand Genetic Position: Chr7, 84.93 cM
• Alliance: Gm2044^em1Meli page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/Cas9 technology deleted exons 1 and 2. RT-PCR confirmed absence of mRNA expression in homozygous ovaries. (J:345849)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gm2044 Mutation: 1 strain or line available

References

• Original: J:345849 Hu K, et al., Interaction of lncRNA Gm2044 and EEF2 promotes estradiol synthesis in ovarian follicular granulosa cells. J Ovarian Res. 2023 Aug 23;16(1):171
• All: 1 reference(s)