Fam171a2^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fam171a2^em1Smoc
• Name: family with sequence similarity 171, member A2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:8187544
• Synonyms: FAM171A2^flox
• Gene: Fam171a2 Location: Chr11:102327807-102338508 bp, - strand Genetic Position: Chr11, 66.29 cM
• Alliance: Fam171a2^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• CRISPR/cas9 mediated recombination created a floxed allele (J:362731)
• Inheritance: Not Specified

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fam171a2 Mutation: 31 strains or lines available

References

• Original: J:362731 Wu KM, et al., Neuronal FAM171A2 mediates alpha-synuclein fibril uptake and drives Parkinson's disease. Science. 2025 Feb 21;387(6736):892-900
• All: 1 reference(s)