Rbbp5^em1Bokz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rbbp5^em1Bokz
• Name: retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit; endonuclease-mediated mutation 1, Bokai Zhu
• MGI ID: MGI:8169574
• Synonyms: Rbbp5^flox
• Gene: Rbbp5 Location: Chr1:132405103-132433397 bp, + strand Genetic Position: Chr1, 57.24 cM
• Alliance: Rbbp5^em1Bokz page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Easi-CRISPR-targeting inserted loxP sites flanking exon 10, which contains the SET/ASH2L binding domain. (J:360830)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rbbp5 Mutation: 56 strains or lines available

References

• Original: J:360830 Kubra S, et al., Epigenetic regulation of global proteostasis dynamics by RBBP5 ensures mammalian organismal health. bioRxiv. 2024 Sep 13
• All: 1 reference(s)