Misp^em1Nsas
Endonuclease-mediated Allele Detail

Summary

• Symbol: Misp^em1Nsas
• Name: mitotic spindle positioning; endonuclease-mediated mutation 1, Nobuya Sasaki
• MGI ID: MGI:8166264
• Gene: Misp Location: Chr10:79656853-79666286 bp, + strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: Misp^em1Nsas page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting produced a null allele. (J:363871)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Misp Mutation: 18 strains or lines available

References

• Original: J:363871 Hiura K, et al., Mitotic Spindle Positioning (MISP) Facilitates Colorectal Cancer Progression by Forming a Complex with Opa Interacting Protein 5 (OIP5) and Activating the JAK2-STAT3 Signaling Pathway. Int J Mol Sci. 2024 Mar 6;25(5)
• All: 1 reference(s)