Nicn1^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nicn1^em1(IMPC)Mbp
• Name: nicolin 1; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:7868159
• Gene: Nicn1 Location: Chr9:108167642-108173697 bp, + strand Genetic Position: Chr9, 59.18 cM, cytoband F2
• Alliance: Nicn1^em1(IMPC)Mbp page
• IMPC: Nicn1 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Deletion
• Mutation details: This allele was generated at University of California, Davis using Cas9 and guides with spacer sequences ATTTTTGCCCAGATAGAACT and CCGCCCTGATCATCGGTGAT that targeted exon(s) ENSMUSE00001659015.1 ENSMUSE00000221503.5 ENSMUSE00000221504.4 ENSMUSE00000221505.4 ENSMUSE00000221507.4 ENSMUSE00000392675.7 ENSMUSE00001340459.2. This resulted in deletion(s) of 2 bp (location: Chr9:108167323-108167324; GRCm39), 4830 bp (location: Chr9:108167593-108172422; GRCm39). This description was generated automatically. Additional molecular information including FASTA sequence support for this allele can be found here: (IMPC Gene page) and viewed in a genome context here: (IMPC Genome Browser). (J:384794)

• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Nicn1 Mutation: 47 strains or lines available

References

• Original: J:265051 MGI and IMPC, MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC). Database Release. 2018-2023
• All: 3 reference(s)