Plaat1^em1Ueda
Endonuclease-mediated Allele Detail

Summary

• Symbol: Plaat1^em1Ueda
• Name: phospholipase A and acyltransferase 1; endonuclease-mediated mutation 1, Natsuo Ueda
• MGI ID: MGI:7868153
• Synonyms: Plaat1^-
• Gene: Plaat1 Location: Chr16:29028447-29049283 bp, + strand Genetic Position: Chr16, 20.01 cM, cytoband B2
• Alliance: Plaat1^em1Ueda page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 genome editing technology was used to target exon 2. (J:343807)

Expression

In Structures Affected by this Mutation:

6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plaat1 Mutation: 19 strains or lines available

References

• Original: J:343807 Rahman SMK, et al., PLAAT1 deficiency alleviates high-fat diet-induced hepatic lipid accumulation in mice. FASEB J. 2023 Jul;37(7):e23032
• All: 1 reference(s)