Col1a1^{tm2(CAG-EGFP,-RNAi:Mirn26)Shzg}
Targeted Allele Detail

Summary

• Symbol: Col1a1^{tm2(CAG-EGFP,-RNAi:Mirn26)Shzg}
• Name: collagen, type I, alpha 1; targeted mutation 2, Sebastian Herzog
• MGI ID: MGI:7857218
• Gene: Col1a1 Location: Chr11:94827050-94843868 bp, + strand Genetic Position: Chr11, 59.01 cM, cytoband D
• Alliance: Col1a1^{tm2(CAG-EGFP,-RNAi:Mirn26)Shzg} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:361360
• Parent Cell Line: KH2 (ES Cell)
• Strain of Origin: (C57BL/6 x 129S4/SvJae)F1

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: FRT-mediated knock-in of a CAG-flox-stop-flox EGFP miR-26 sponge (Mirn26a-1, Mirn26a-2, and Mirn26b) cassette into the gene locus. (J:361360)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Col1a1 Mutation: 166 strains or lines available

References

• Original: J:361360 Hutter K, et al., The miR-26 family regulates early B cell development and transformation. Life Sci Alliance. 2022 Aug;5(8):e202101303
• All: 1 reference(s)