Tg(CMV*-RFP1)6Flmg
Transgene Detail

Summary

• Symbol: Tg(CMV*-RFP1)6Flmg
• Name: transgene insertion 6, Biomedical Sciences Research Center Al Fleming
• MGI ID: MGI:7855513
• Synonyms: Tg(CMV-CAGA-RFP1)6
• Transgene: Tg(CMV*-RFP1)6Flmg Location: unknown
• Alliance: Tg(CMV*-RFP1)6Flmg page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inducible, Reporter)
• Mutation: Insertion
• Mutation details: In this reporter line, the red fluorescent protein RFP1 is expressed under the control of a synthetic Smad2/3-induced promoter. The core element of this promoter consist of 12 repeats of the well characterized CAGA element, the Smad2/3 binding element. Six lines where generated with line 6 selected as the representative line. (J:347441)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:347441 Stavropoulos A, et al., Coordinated activation of TGF-beta and BMP pathways promotes autophagy and limits liver injury after acetaminophen intoxication. Sci Signal. 2022 Jun 28;15(740):eabn4395
• All: 1 reference(s)