Mtln^em1Zshm
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mtln^em1Zshm
• Name: mitoregulin; endonuclease-mediated mutation 1, Shi-Mei Zhuang
• MGI ID: MGI:7852340
• Gene: Mtln Location: Chr2:127633308-127634408 bp, - strand Genetic Position: Chr2, 62.1 cM
• Alliance: Mtln^em1Zshm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR-targeting of exon 1 inserted a single base pair (T) resulting in a premature stop codon after the fifth codon. (J:285451)

Expression

In Mice Carrying this Mutation:

9 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mtln Mutation: 6 strains or lines available

References

• Original: J:285451 Lin YF, et al., A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation. Cell Death Dis. 2019 Jul 11;10(7):528
• All: 2 reference(s)