Rnaseh1^em1.1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rnaseh1^em1.1Gpt
• Name: ribonuclease H1; endonuclease-mediated mutation 1.1, GemPharmatech Co., Ltd
• MGI ID: MGI:7852139
• Gene: Rnaseh1 Location: Chr12:28699601-28709588 bp, + strand Genetic Position: Chr12, 10.99 cM, cytoband A3
• Alliance: Rnaseh1^em1.1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR-targeting floxed allele exons 2 and 3. Recombination removed the floxed exons to produced a null allele. (J:360686)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rnaseh1 Mutation: 30 strains or lines available

References

• Original: J:360686 Jiang Y, et al., Genome-wide map of R-loops reveals its interplay with transcription and genome integrity during germ cell meiosis. J Adv Res. 2023 Sep;51:45-57
• All: 1 reference(s)