Il17ra^em1Hmsa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Il17ra^em1Hmsa
• Name: interleukin 17 receptor A; endonuclease-mediated mutation 1, Holly Algood
• MGI ID: MGI:7840386
• Gene: Il17ra Location: Chr6:120440143-120460692 bp, + strand Genetic Position: Chr6, 56.95 cM
• Alliance: Il17ra^em1Hmsa page

Mutation origin

• Strain of Origin: FVB/N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted 82 bp resulting in a frameshift. (J:360577)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Il17ra Mutation: 47 strains or lines available

References

• Original: J:360577 Brackman LC, et al., IL-17 receptor A functions to help maintain barrier integrity and limit activation of immunopathogenic response to H. pylori infection. Infect Immun. 2024;92(1):e0029223
• All: 2 reference(s)