Pibf1^m1Bei
Chemically induced Allele Detail

Summary

• Symbol: Pibf1^m1Bei
• Name: progesterone immunomodulatory binding factor 1; mutation 1, David R Beier
• MGI ID: MGI:7798750
• Synonyms: line 11
• Gene: Pibf1 Location: Chr14:99336860-99491929 bp, + strand Genetic Position: Chr14, 49.27 cM, cytoband E2.1
• Alliance: Pibf1^m1Bei page

Mutation origin

• Strain of Origin: A/J

Mutation description

• Allele Type: Chemically induced (ENU) (Null/knockout)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a splice donor mutation in intron 9: NM_029320.4: c.1223+2T>C; p.Arg366. Transcripts from this allele skip exon 9, resulting in the loss of the coil-coiled domain in the encoded protein. (J:199782, J:371501)

Disease models

Expression

In Structures Affected by this Mutation:

17 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pibf1 Mutation: 54 strains or lines available

References

• Original: J:371501 Pimentel L, et al., Centriolar protein PIBF1 is required for craniofacial and forebrain development. Dev Biol. 2025 Aug 5;527:55-64
• All: 2 reference(s)