Rr805^em1Mostr
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rr805^em1Mostr
• Name: regulatory region 805; endonuclease-mediated mutation 1, Marco Osterwalder
• MGI ID: MGI:7797749
• Synonyms: SV-Enh^delta
• Gene: Rr805 Location: Chr3:66704670-66707155 bp, . strand Genetic Position: Chr3, Syntenic
• Alliance: Rr805^em1Mostr page

Mutation origin

• Strain of Origin: FVB/NRj

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intergenic deletion
• Mutation details: CRISPR-targeting deleted a 4.4 kb fragment containing the +325A cardiac sinus venosus (SV) enhancer (SV-Enh; chr3:66561862-66566303 (GRCm39/mm39)). (J:355648)

Expression

In Mice Carrying this Mutation:

7 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rr805 Mutation: 0 strains or lines available

References

• Original: J:355648 Abassah-Oppong S, et al., A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival. Nat Commun. 2024 Oct 10;15(1):8793
• All: 1 reference(s)