Jak2^em3Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Jak2^em3Cya
• Name: Janus kinase 2; endonuclease-mediated mutation 3, Cyagen Biosciences
• MGI ID: MGI:7797735
• Synonyms: Jak2^em1(V617F)
• Gene: Jak2 Location: Chr19:29229228-29290480 bp, + strand Genetic Position: Chr19, 23.73 cM
• Alliance: Jak2^em3Cya page

Mutation origin

• Strain of Origin: C57BL/6JCya

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Nucleotide substitutions
• Mutation details: CRISPR-targeting introducing a homologous mutation to the human V617F mutation into the mouse gene. This strain is homozygous lethal. (J:326541)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Jak2 Mutation: 60 strains or lines available

References

• Original: J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022
• All: 1 reference(s)