Tg(Atoh1-tTA2)B40Alj
Transgene Detail

Summary

• Symbol: Tg(Atoh1-tTA2)B40Alj
• Name: transgene insertion B40, Alexandra L Joyner
• MGI ID: MGI:7788990
• Synonyms: Atoh1-tTA
• Transgene: Tg(Atoh1-tTA2)B40Alj Location: unknown
• Alliance: Tg(Atoh1-tTA2)B40Alj page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Transactivator)
• Mutation: Insertion
• Tg(Atoh1-tTA2)B40Alj expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Atoh1 (MGI:104654)

• Mutation details: The transgene was designed with a 1.4 kb mouse atonal bHLH transcription factor 1 (Atoh1) 3' enhancer (and a beta-globin minimal promoter) sequence upstream of a tetracycline-regulated transactivator gene (tTA2). Line B40 was selected and used,. (J:101977, J:292768)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:292768 Willett RT, et al., Cerebellar nuclei excitatory neurons regulate developmental scaling of presynaptic Purkinje cell number and organ growth. Elife. 2019 Nov 19;8:e50617
• All: 3 reference(s)