Ighg1^{tm1(IGHG4)Smoc}
Targeted Allele Detail

Summary

• Symbol: Ighg1^{tm1(IGHG4)Smoc}
• Name: immunoglobulin heavy constant gamma 1 (G1m marker); targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7786879
• Synonyms: Ighg1^{tm1(hIGHG4)Smoc}
• Gene: Ighg1 Location: Chr12:113290161-113294143 bp, - strand Genetic Position: Chr12, 62.1 cM
• Alliance: Ighg1^{tm1(IGHG4)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Ighg1^{tm1(IGHG4)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  IGHG4 (3503)

  Ighg	(MGI:2144967)
  Ighg1	(MGI:96446)
  Ighg2a	(MGI:96443)
  Ighg2b	(MGI:96445)
  Ighg2c	(MGI:2686979)
  Ighg3	(MGI:2144790)

• The endogenous mouse Ighg1 gene was replaced by human IGHG4 gene. (J:238766)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ighg1 Mutation: 29 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)