Cftr^{tm1(CFTR)Smoc}
Targeted Allele Detail

Summary

• Symbol: Cftr^{tm1(CFTR)Smoc}
• Name: cystic fibrosis transmembrane conductance regulator; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:7786835
• Synonyms: Cftr^{tm1(hCFTR)Smoc}
• Gene: Cftr Location: Chr6:18170686-18322767 bp, + strand Genetic Position: Chr6, 8.1 cM, cytoband A3
• Alliance: Cftr^{tm1(CFTR)Smoc} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:238766
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Targeted (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Cftr^{tm1(CFTR)Smoc} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CFTR (1080)

  Cftr	(MGI:88388)

• The endogenous mouse Cftr gene was replaced by human CFTR gene. (J:238766)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cftr Mutation: 98 strains or lines available

References

• Original: J:238766 Shanghai Model Organisms Center, Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China. MGI Direct Data Submission. 2017
• All: 1 reference(s)