Ubiad1^tm1Msnt
Targeted Allele Detail

Summary

• Symbol: Ubiad1^tm1Msnt
• Name: UbiA prenyltransferase domain containing 1; targeted mutation 1, Massimo Santoro
• MGI ID: MGI:7786646
• Gene: Ubiad1 Location: Chr4:148518952-148529217 bp, - strand Genetic Position: Chr4, 78.76 cM, cytoband E1
• Alliance: Ubiad1^tm1Msnt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:354211
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Insertion
• Mutation details: The targeting construct introduced a neomycin resistance cassette at the ATG transcriptional initiation site. (J:354211)
• Inheritance: Not Specified

Expression

In Mice Carrying this Mutation:

5 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ubiad1 Mutation: 24 strains or lines available

Notes

Lentiviral gene trap injected into zygotes.

References

• Original: J:354211 Tosi G, et al., Cancer cell stiffening via CoQ(10) and UBIAD1 regulates ECM signaling and ferroptosis in breast cancer. Nat Commun. 2024 Sep 18;15(1):8214
• All: 1 reference(s)