Rpl13a^tm2.1Mazu
Targeted Allele Detail

Summary

• Symbol: Rpl13a^tm2.1Mazu
• Name: ribosomal protein L13A; targeted mutation 2.1, Barsanjit Mazumder
• MGI ID: MGI:7785043
• Gene: Rpl13a Location: Chr7:44774987-44778169 bp, - strand Genetic Position: Chr7, 29.14 cM
• Alliance: Rpl13a^tm2.1Mazu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:355494
• Parent Cell Line: iTL IC1 (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced exons 2 through 7 with an FRT- and loxP-flanked neomycin resistance cassette. Flp-mediated recombination removed the selection cassette. (J:355494)

Expression

In Mice Carrying this Mutation:

3 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rpl13a Mutation: 40 strains or lines available

References

• Original: J:355494 Kour R, et al., Loss of function of ribosomal protein L13a blocks blastocyst formation and reveals a potential nuclear role in gene expression. FASEB J. 2023 Dec;37(12):e23275
• All: 1 reference(s)