Tg(Rorc-tdTomato)1Goet
Transgene Detail

Summary

• Symbol: Tg(Rorc-tdTomato)1Goet
• Name: transgene insertion 1, Jeremy Goettel
• MGI ID: MGI:7783508
• Transgene: Tg(Rorc-tdTomato)1Goet Location: unknown
• Alliance: Tg(Rorc-tdTomato)1Goet page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Reporter)
• Mutation: Insertion
• Mutation details: A transgene contains tdTomato-BGHpA-FRT-neomycin-FRT cassette inserted into the open reading frame of the ROR gamma isoform (Rorc), 3' of the ATG start site in BAC clone RP23-263K17. The neomycin cassette was removed by FLP-mediated recombination leaving one FRT site. (J:101977, J:368625)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:368625 Li J, et al., Interleukin-10 production by innate lymphoid cells restricts intestinal inflammation in mice. Mucosal Immunol. 2025 Feb 21
• All: 2 reference(s)