Kat6b^tm1Avo
Targeted Allele Detail

Summary

• Symbol: Kat6b^tm1Avo
• Name: K(lysine) acetyltransferase 6B; targeted mutation 1, Anne K Voss
• MGI ID: MGI:7768126
• Gene: Kat6b Location: Chr14:21549284-21722546 bp, + strand Genetic Position: Chr14, 11.73 cM
• Alliance: Kat6b^tm1Avo page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: Bruce 4 (ES Cell)
• Strain of Origin: B6.Cg-Thy1^a

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting vector was designed to insert loxP flanking the exon 2, containing the ATG site. (J:101977, J:348717)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kat6b Mutation: 109 strains or lines available

References

• Original: J:348717 Bergamasco MI, et al., The histone acetyltransferase KAT6B is required for hematopoietic stem cell development and function. Stem Cell Reports. 2024 Apr 9;19(4):469-485
• All: 2 reference(s)