Pirnac4^em2Pdz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pirnac4^em2Pdz
• Name: piRNA cluster 4; endonuclease-mediated mutation 2, Phillip Zamore
• MGI ID: MGI:7767968
• Synonyms: pi7^em2Pdz
• Gene: Pirnac4 Location: unknown Genetic Position: Chr7, Syntenic

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting removed the piRNA cluster located on chromosome 7 (chr7:73816243-73816716; GRCm39). (J:357900)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pirnac4 Mutation: 2 strains or lines available

References

• Original: J:357900 Cecchini K, et al., Mouse Pachytene piRNAs Cleave Hundreds of Transcripts, But Alter the Steady-State Abundance of Only a Minority of Targets. bioRxiv. 2024
• All: 2 reference(s)